Cryotherapy uses liquid nitrogen to super-freeze the tissue in order to destroy abnormal or diseased tissues, like warts, skin tags, moles, etc. During the procedure, a local anaesthesia cream is applied to numb the area being treated. Then the doctor applies the liquid nitrogen to the wart using a probe or a cotton swab. Liquid nitrogen can also be sprayed directly on the wart. After that the destroyed tissue is removed. Some warts may require multiple treatments every 7-10 days. Depending on the treatment area, you may need to rest for up to a week (eg. in case of sites like the feet). Otherwise, there is little downtime, and besides caring for the treated area, you can return to your daily activities.